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MG-115 Size:Contact [email protected] for quotation CAS Number: 79055-68-8

SKU: 1951075033

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Description

CAS Number: 79055-68-8

7a-dihydrogenio-1

11aH-cyclopenta[a]phenanthren-7-yl sodium sulfate

anti-inflammatory and chemotherapeutic effects in vivo

Formula: C28H34N6O5

MG-115 Size:Contact [email protected] for quotation CAS Number: 79055-68-8MG 115 (Z Leu Leu Nva H) is a potent, reversible peptide aldehyde inhibitor of proteasome chymotrypsin like and caspase like activities. It induces p53 dependent apoptosis. Blockade of proteasomal degradation by MG115 can activate autophagy. Treatment with proteasome inhibitors Z Leu Leu Nva H (MG 115) or Z Leu Leu Leu H (MG 132) prevented the accelerated degradation of these mutant receptors, resulting in increased amounts of the mutant receptors in

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