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Solubility: DMSO : ≥ 100 mg/mL (217
58(12):4976-4983
Epub 2013 Mar 1
thereby selectively and irreversibly blocking glucose uptake
CAS Number: 26647-82-5
A-192621 - CAS# 195529-54-5 0228 Solubility: DMSO : ≥ 100A 192621 is a potent, nonpeptide, orally active and selective endothelin B (ETB) receptor antagonist with an IC50 of 4. 5 nM and a Ki of 8. 8 nM. The selectivity of A 192621 is 636 fold higher than ETA (IC50 of 4280 nM and Ki of 5600 nM). A 192621 promotes apoptosis in PASMCs. A 192621 alos causes elevation of arterial blood pressure and an elevation in the plasma ET 1 level. Product information CAS Number: 195529 54 5 Molecular Weight: 558. 66