DBCO-PEG4-MMAF X (FG9202) Smiles: N[C@@H](CCCN=C(N)N)C(=O)N1CCC[C@H]1C(=O)N1C[C@H](O)C[C@H]1C(=O)NCC(=O)N[C@@H](CC1C=CC=CC=1)C(=O)N[C@@H](CO)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC1C=CC=CC=1)C(=O)N[C@@H](CCCN=C(N)N)C(O)=O

Smiles: N[C@@H](CCCN=C(N)N)C(=O)N1CCC[C@H]1C(=O)N1C[C@H](O)C[C@H]1C(=O)NCC(=O)N[C@@H](CC1C=CC=CC=1)C(=O)N[C@@H](CO)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC1C=CC=CC=1)C(=O)N[C@@H](CCCN=C(N)N)C(O)=O

Smiles: OC(=O)C1CNCCC=1

24 hours) induces apoptosis in SGC-7901 cells

29)25(35)30-22(18-37-17-21-12-8-5-9-13-21)24(34)33-15-14-23-28(19-33

a synthetic 13 amino acid peptide

DBCO-PEG4-MMAF X (FG9202) Smiles: N[C@@H](CCCN=C(N)N)C(=O)N1CCC[C@H]1C(=O)N1C[C@H](O)C[C@H]1C(=O)NCC(=O)N[C@@H](CC1C=CC=CC=1)C(=O)N[C@@H](CO)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC1C=CC=CC=1)C(=O)N[C@@H](CCCN=C(N)N)C(O)=ODBCO PEG4 MMAF is a drug linker conjugate for ADC with potent antitumor activity by using the tubulin polymerization inhibitor, MMAF, linked via the cleavable linker DBCO PEG4. Product information CAS Number: 2360411 65 8 Molecular Weight: 1266. 56 Formula: C69H99N7O15 Chemical Name: (2S) 2 [(2R) 2 [(R) [(2S) 1 [(3R,4S,5S) 4 [(2S) 2 [(2S) 2 [1 (4 {2 azatricyclo[10. 4. 0. 0,]hexadeca 1(16),4,6,8,12,14 hexaen 10 yn 2 yl} 4 oxobutanamido) N methyl