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a variety of cell lines
migration with an IC50 of 15
PubMed Central PMCID: PMC2797793
Combining PDMP and GNF-2 eliminated transplanted-CML-T315I-mutants in vivo and dose dependently sensitized primary cells from CML T315I patients to GNF-2-induced proliferation inhibition and apoptosis
Smiles: CN(C)C(=O)OC1=CC(=CC=C1)NC(=O)C1(CN)CCN(CC1)C1N=CN=C2NC=C(C)C=12
GW3965 HCl - CAS# 405911-17-3 size:2mg solid a variety of cell linesGW3965 HCl, CAS No. 405911 17 3, is a liver X receptor agonist. GW3965 represses the production of pro inflammatory cytokines by murine mast cells. GW3965 improves recovery from mild repetitive traumatic brain injury in mice partly through apolipoprotein E. GW3965 reduces tissue factor production and inflammatory responses in human islets in vitro. GW3965 dose dependently regulates lps mediated liver injury and modulates posttranscriptional TNF alpha