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CHMFL-ABL-053 inhibited the proliferation of CML cell lines K562 (GI50 = 14 nM)
Fenebrutinib (GDC-0853) inhibits CD69 expression on CD19+ B cells in human whole blood with an IC50 of 8
Comparative pharmacokinetics of levamisole-oxyclozanide combination in sheep and goats following per os administration
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Seviteronel (VT-464)
VU0364572 (trifluoroacetate salt) 247egeline CHMFL-ABL-053 inhibited the proliferation ofIC50: 477 172 nM VU0364572 is a M1 agonist. Alzheimer's disease (AD) is the leading cause of dementia worldwide, and no disease modifying therapy is availables. Selective M1 muscarinic acetylcholine receptor activation is an attractive mechanism for AD therapy since M1 mediates key effects on cognition, memory, and behavior and has potential for disease modifying effects on A formation and tau phosphorylation. In vitro: Previous study found that
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