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GSK484 hydrochloride ty H 3-thiazolidin-2-ylidene]methyl}-1

SKU: 15415977507

4.0
USD120.00 USD151.00

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Description

3-thiazolidin-2-ylidene]methyl}-1

which is a strong antioxidant agent

Smiles: COC1C=CC(=CC=1)C1N=C(C2C=C(C=C(C=2)C(F)(F)F)C(F)(F)F)N(CC2C=CC(=CC=2)C(N)=O)C=1C1C=CC(=CC=1)OC

CID 49852229

Smiles: CN(C)C(=O)C1=CC2NC(=O)/C(=C(\NC3=CC(CN(C)C)=CC=C3)/C3C=CC=CC=3)/C=2C=C1

GSK484 hydrochloride ty H 3-thiazolidin-2-ylidene]methyl}-1GSK484 hydrochloride is a selective and reversible peptidylarginine deiminase 4 (PAD4) inhibitor. GSK484 hydrochloride demonstrates high affinity binding to PAD4 with IC50s of 50 nM in the absence of Calcium. In the presence of 2 mM Calcium, notably lower potency (250 nM) is observed. Product information CAS Number: 1652591 81 5 Molecular Weight: 510. 03 Formula: C27H32ClN5O3 Chemical Name: (3S,4R) 3 amino 1 {2 [1 (cyclopropylmethyl) 1H indol 2 yl] 7

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