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which inhibits RANKL-induced osteoclast formation and bone resorption in vitro and prevents LPS-induced bone loss in vivo
Formula: C30H40ClN7O3S
Smiles: CC1C=CC(=CC=1)S(=O)(=O)N[C@@H](CC1=CNC2=CC=CC=C12)C(=O)NC1=NC(=CS1)C1C=CC(=CC=1)OC
InChiKey: RDJAFOWISVMOJY-PWNZVWSESA-N
InChi: InChI=1S/C26H26F4N4O3/c27-19-8-4-7-17-20(15-5-2-1-3-6-15)32-23(25(37)33-21(17)19)34-24(36)16(11-12-26(28
GW0742 606STYSLSSTLTLSK which inhibits RANKL-induced osteoclast formationGW0742 is a potent PPAR and PPAR agonist, with an IC50 of 1 nM for human PPAR in binding assay, and EC50s of 1 nM, 1. 1 M and 2 M for human PPAR, PPAR, and PPAR, respectively. Product information CAS Number: 317318 84 6 Molecular Weight: 471. 49 Formula: C21H17F4NO3S2 Chemical Name: 2 {4 [({2 [3 fluoro 4 (trifluoromethyl)phenyl] 4 methyl 1,3 thiazol 5 yl}methyl)sulfanyl] 2 methylphenoxy}acetic acid Smiles:
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