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PubMed PMID: 15999992
Celastrol significantly inhibits the proteasomal chymotrypsin activity in PC-3 cells in a concentration-dependent manner
Smiles: OC(=O)CCCC(=O)NC1=CC=CC2=C1C(=O)N(C1CCC(=O)NC1=O)C2=O
PMID: 26236920
InChiKey: GQYBNVXJQVIRGC-UHFFFAOYSA-N
Lycorine - CAS# 476-28-8 2171 PubMed PMID: 15999992Lycorine is a natural alkaloid extracted from the Amaryllidaceae plant. Lycorine is a potent and orally active SCAP inhibitor with a Kd value 15. 24 nM. Lycorine downregulates the SCAP protein level without changing its transcription. Lycorine is also a melanoma vasculogenic inhibitor. Lycorine can be used for the study of prostate cancer and metabolic diseases. Product information CAS Number: 476 28 8 Molecular Weight: 287. 31 Formula: C16H17NO4
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