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ERK1/2 (P-ERK1/2) by SJ000291942
TYP (50 mg/kg
2) and antagonized the dopamine induction of [(35)S]GTPgammaS binding (pA2=9
inducing apoptosis
3)4)27(38)33-25(20-11-7-6-8-12-20)29(39)35-16-10-15-24(35)28-32-23(18-42-28)26(37)21-13-9-14-22(36)17-21/h9
Delamanid (OPC-67683) - CAS# 681492-22-8 60233 ERK1/2 (P-ERK1/2) by SJ000291942Delamanid (OPC 67683), CAS No. 681492 22 8, also known as OPC 67683, is a drug for the treatment of multi drug resistant tuberculosis. It works by blocking the synthesis of mycolic acids in Mycobacterium tuberculosis, the organism which causes tuberculosis, thus destabilising its cell wall. The drug is approved in the EU. Delamanid inhibits the synthesis of mycolic acids, crucial component of the cell wall of the Mycobacterium tuberculosis complex.