Valganciclovir Hydrochloride uhzin CC(C)CCC[C@@H](C)CCC[C@@H](C)CCC/C(/C)=C/COC(=O)CC[C@H]1[C@H](C)C2C=C3[N-]C(=CC4=NC(=CC5[N-]C6=C(C(=O)[C@H](C(=O)OC)C6=C1N=2)C=5C)[C@H](CC)[C@H]4C)C(C(C)=O)=C3C

CC(C)CCC[C@@H](C)CCC[C@@H](C)CCC/C(/C)=C/COC(=O)CC[C@H]1[C@H](C)C2C=C3[N-]C(=CC4=NC(=CC5[N-]C6=C(C(=O)[C@H](C(=O)OC)C6=C1N=2)C=5C)[C@H](CC)[C@H]4C)C(C(C)=O)=C3C

7a-hexahydrocyclopenta[c]pyran-4-carboxylate

Molecular Weight: 291

but is inactive against HuT 78 and Jurkat E6-1 with IC50 values of >10 uM

a therapeutic agent

Valganciclovir Hydrochloride uhzin CC(C)CCC[C@@H](C)CCC[C@@H](C)CCC/C(/C)=C/COC(=O)CC[C@H]1[C@H](C)C2C=C3[N-]C(=CC4=NC(=CC5[N-]C6=C(C(=O)[C@H](C(=O)OC)C6=C1N=2)C=5C)[C@H](CC)[C@H]4C)C(C(C)=O)=C3CValganciclovir is an L valyl ester (prodrug) of ganciclovir that exists as a mixture of two diastereomers. After oral administration, both diastereomers are rapidly converted to ganciclovir by intestinal and hepatic esterases. Ganciclovir is a synthetic analogue of 2' deoxyguanosine, which inhibits replication of human CMV in cell culture and in vivo. The reported EC50 values of ganciclovir that inhibit human CMV replication in cell culture