(Rac)-Calpain Inhibitor XII inib bromide Chemical Name: 4-methyl-4-azatetracyclo[13

Chemical Name: 4-methyl-4-azatetracyclo[13

a 3rd Generation EGFR-TKI

6R)-2-{3-hydroxy-5-[(E)-2-(4-methoxyphenyl)ethenyl]phenoxy}-6-(hydroxymethyl)oxane-3

InChiKey: KWTQSFXGGICVPE-WCCKRBBISA-N

1 nM and 20

(Rac)-Calpain Inhibitor XII inib bromide Chemical Name: 4-methyl-4-azatetracyclo[13(Rac) Calpain Inhibitor XII is a reversible and selective inhibitor of calpain I ( calpain, Ki=19 nM). (Rac) Calpain Inhibitor XII has lower affinities for calpain II (m calpain, Ki=120 nM) and cathepsin B (Ki=750 nM). (Rac) Calpain Inhibitor XII has the potential for studying the role of calpains in diverse processes, including neutrophil chemotaxis, neuronal signaling, and cardiac response to injury. Product information CAS Number: 181769 57 3