PIK-III - CAS# 1383716-40-2 6053 10 µM KGN in 4

10 µM KGN in 4 µl of saline was intra-articularly (IA) delivered into mice on days 7 and 21 in the collagenase VII–induced model and the acute surgical model

8mg/mL in DMSO

5-10 µM final concentration in various in vitro assays

Rupaimoole R

Bromosporine (1 µM) accelerates FRAP recovery of BRD4 and CREBBP

PIK-III - CAS# 1383716-40-2 6053 10 µM KGN in 4PIK III, also known as VPS34 IN2, CAS No. 1383716 40 2, is a VPS34 inhibitor which blocks autophagy and uncovers a role for NCOA4 in ferritin degradation and iron homeostasis in vivo. PIK III binds a unique hydrophobic pocket not present in related kinases such as PI(3)K. PIK III acutely inhibits autophagy and de novo lipidation of LC3, and leads to the stabilization of autophagy substrates. . Product information CAS Number: 1383716 40 2 Molecular