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Ciclopirox is a broad-spectrum antifungal with anti-inflammatory properties effective against the yeast implicated in seborrhoeic dermatitis
Smiles: C/C(=C\C(O)=O)/C=C/C=C(\C)/C=C/C1=C(C)C(C)=C(C=C1C)OC
25(10):3164-3175
LY-303511 enhances TRAIL sensitivity of SHEP-1 neuroblastoma cells via H2O2-MAPK activation and up-regulation of death receptors
(2004) Cell
PP2 - CAS# 172889-27-9 Catalog No.:M9704-10 Ciclopirox is a broad-spectrum antifungalPP2, also known as AG 1879, is a substance that has frequently been used in cancer research as a "selective" inhibitor for Src family kinases. It strongly inhibits the kinases Lck (IC50=4 nM), Fyn (5 nM) and Hck (5 nM), shows weaker inhibition of EGFR (480 nM) and practically no inhibition of ZAP 70 (100 M) and JAK2 (50 M). Despite its extensive use as a Src selective inhibitor, recent research has shown that PP2 is non selective and inhibits many
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