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CAS Number: 2041073-22-5
reduces activity of AST and ALT in TCDD-treated mice
(2015) Cell
Ichikawa S
J Cancer Res Clin Oncol
Biperiden ader-3 CAS Number: 2041073-22-5AZD8186 is and inhibitor of the beta isoform of phosphoinositide 3 kinase (PI3K), with potential antineoplastic activity. Upon administration, PI3Kbeta inhibitor AZD8186 selectively inhibits the activity of PI3Kbeta in the PI3K Akt mTOR signaling pathway, which may result in a decrease of tumor cell proliferation. It also induces cell death in PI3K expressing cancer cells. By specifically targeting class I PI3K beta, this agent may be more efficacious
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