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PF-03716556 Size:2mg solid CAS Number: 1640294-30-9

SKU: 34834802139

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Description

CAS Number: 1640294-30-9

6)7)47(64)58-25-36(60)22-38(58)46(63)52-24-32-8-10-34(11-9-32)43-29(2)53-27-68-43/h8-15

Smiles: [O-][N+](=O)C1C=CC(=CC=1)NC1N=C(N=C(N=1)N1CCOCC1)N1CCOCC1

SAM486A treatment resulted in the rapid accumulation of proapoptotic proteins p53 and Mdm2

Chemical Name: (R)-1-(3-(3-amino-6-(2-fluoro-5-isopropoxyphenyl)pyrazine-2-carboxamido)pyridin-4-yl)piperidine-3-carboxylic acid

PF-03716556 Size:2mg solid CAS Number: 1640294-30-9PF 03716556 is a potent, and selective acid pump antagonist for the treatment of gastroesophageal reflux disease. PF 03716556 demonstrated 3 fold greater inhibitory activity than revaprazan. PF 03716556 did not display any species differences, exhibiting highly selective profile including the canine kidney Na(+), K(+) ATPase. Kinetics experiments revealed that PF 03716556 has a competitive and reversible mode of action. Product information CAS Number:

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