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CAS Number: 1638970-44-1
5R)-2-({[(2R
Formula: C34H28N4O5
Smiles: CC(C)NC[C@@H](O)COC1=CC=C(CC(N)=O)C=C1
3E)-5-hydroxy-3-methylpenta-1
S-(2-aminoethyl) Isothiourea (dihydrobromide) 684PADS tetrasodium CAS Number: 1638970-44-1S (2 aminoethyl) Isothiourea (dihydrobromide) is a potent and non selective inhibitor of NOS with Ki values of 1. 8, 2. 1, and 0. 59 M for human nNOS, eNOS, and iNOS, respectively . In the brain, nitric oxide (NO), which is synthesized from L arginine (Arg) by NO synthase (NOS), acts as both an intra and an intercellular second messenger. Nitric oxide synthase (iNOS, eNOS, and nNOS) catalyzed the production of NO in the two step oxidation of L
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