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4 and 290 nM at pH 8
which is potent and selective against BaF3-tel-c-KIT (IC50 of 4 nM) and a broad spectrum of drug-resistant mutants (IC50 of 8 nM for BaF3-tel-c-KIT-T670I) with improved bioavailability
Emanuele E
6 hours) specifically reduces the protein levels of HIF-1α in a dose-dependent manner under hypoxic conditions
SAFit1 (1-1000 nM) potently stimulates neurite outgrowth in two neuronal cell lines (N2a and SH-SY5Y) as well as in primary hippocampal neurons
ML-290 0191584 maleate 4 and 290 nM atML 290 is a first in class and potent relaxin insulin like family peptide receptor (RXFP1) agonist and activator of anti fibrotic genes, with an EC50 of 94 nM. ML290 is a biased allosteric agonist at the relaxin receptor RXFP1. Product information CAS Number: 1482500 76 4 Molecular Weight: 506. 49 Formula: C24H21F3N2O5S Chemical Name: 2 (propan 2 yloxy) N {2 [(3 trifluoromethanesulfonylphenyl)carbamoyl]phenyl}benzamide Smiles:
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