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Chemical Name: 2H-1
Transfection of Poly (I:C) into NIT-1 cells has been used as a model of intracellular dsRNA-induced β cell apoptosis
InChi: InChI=1S/C47H73NO17
Treatment of P
InChiKey: DFBIRQPKNDILPW-CIVMWXNOSA-N
CpdA Size:Contact [email protected] for quotation Chemical Name: 2H-1CpdA is a non steroidal selective glucocorticoid receptor modulator. It is an aziridine precursor that can infiltrate cells and is translocated to the nucleus. It inhibits glucocorticoid receptor dimerization, which prevents transcription of gene targets such as NF B and subsequent cytokines through transrepression. Studies have shown contradictory results for binding affinity of CpdA compared with dexamethasone that were either higher (4 fold, IC50 =
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