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CC1=CC=CN2C(=O)C(=CN=C21)C1=N[N-]N=N1
Chemical Name: 4-(4-(1-methyl-1H-pyrazol-4-yl)-1-(2-(1-methyl-1H-pyrazol-4-yl)ethyl)-1H-imidazol-5-yl)benzonitrile
Thalidomide-propargyl is the Thalidomide-based Cereblon ligand used in the recruitment of CRBN protein
Epub 2010 Apr 26
1369773-39-6
20(S)-Hydroxycholesterol Catalog No.:M11818-2 CC1=CC=CN2C(=O)C(=CN=C21)C1=N[N-]N=N120(S) hydroxyCholesterol (20 Hydroxycholesterol) is an allosteric activator of the oncoprotein smoothened (Smo) that activates the hedgehog (Hh) signaling pathway with an EC50 of 3 M in a gene transcription reporter assay using NIH3T3 cells. Product information CAS Number: 516 72 3 Molecular Weight: 402. 65 Formula: C27H46O2 Synonym: 20 Hydroxycholesterol Chemical Name: (1S, 3aS, 3bS, 7S, 9aR, 9bS, 11aS) 1 [(2S) 2 hydroxy 6 methylheptan 2 yl] 9a, 11a
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