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Dickinson BC
InChi: InChI=1S/C15H18N2O/c1-3-11-10-6-9(2)8-15(11
Smiles: CC(C)(C)NC(=O)C1=CN=CN1C1CCN(CC1)C1C=CC(=CN=1)C1=NN=C(O1)C(F)(F)F
Geranyl acetate exhibits significant anti-cancer activity against colo-205 cancer cell line with IC50 value of 30 μM
Chemical Name: 4-[(6
AZD 5153 Catalog No.:M22444-C Dickinson BCTarget: BRD4 IC50: 5 nM AZD5153 is a potent, selective, and orally available inhibitor of the bromodomain and extraterminal (BET) protein BRD4, with the IC50 value of 5 nM. AZD5153 could simultaneously ligate two bromodomains in BRD4, and exert antitumor activity in multiple xenograft tumor models . In Vitro: A quantitative immuno fluorescent assay in U2OS cells revealed that AZD5153 could significantly disrupt BRD4 foci, with the IC50 value of 1. 7