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By the oral route
InChi: InChI=1S/C24H23N5O2/c1-15-12-18-17(22(25)30)8-5-9-21(18)29(15)24-27-20-10-11-31-14-19(20)23(28-24)26-13-16-6-3-2-4-7-16/h2-9
2008 Mar 27
Methods of treatment and combination therapies using gcase activator heterobicyclic and related compounds
8 μM) induces the expression of PD-L1 in THP1 cells and in primary human peripheral blood mononuclear cells in a STING-dependent manner
LY-411575 (isomer 3) nserin By the oral routeLY 411575 isomer 3, is an isomer of LY411575, which is a potent, cell permeable secretase inhibitor (IC50= 0. 078 nM 0. 082 nM (in membrane assay in cell based secretase assays)) and also inhibits Notch clevage (IC50= 0. 41 nM). Product information CAS Number: 2070009 28 6 Molecular Weight: 479. 48 Formula: C26H23F2N3O4 Synonym: LY411575 isomer 3 LY 411575 isomer 3 Chemical Name: (2R) 2 [(2R) 2 (3, 5 difluorophenyl) 2 hydroxyacetamido] N [(10S) 8
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