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DY131 could potentiate the ERRgamma-induced growth inhibition in LNCaP-ERRgamma and DU145-ERRgamma cells in a dose-dependent manner
InChi: InChI=1S/C14H17N5O2S/c20-13(19-6-2-1-3-7-19)9-15-14(21)16-10-4-5-11-12(8-10)22-18-17-11/h4-5
5106–5117
(2014) AACR San Diego
It was developed by the pharmaceutical company Boehringer Ingelheim
TIC10 isomer nib (AMG-706) DY131 could potentiate the ERRgamma-inducedTIC10 isomer is an isomer and the "inactive version" of TIC10. TIC 10 isomer was introduced to the research community since it was structurally wrong assigned as the bioactive TIC 10 during early stage development of TIC 10 (now called ONC 201). TIC 10 isomer was found to be inactive, which did not reduce the viability of cancer cells. TIC 10 isomer may be used as a reference compound to compare with ONC 201. Product information CAS Number: 41276 02 2
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