Y 11 Size:Contact [email protected] for quotation Smiles: CN(C)[C@H]1C[C@@H](C)O[C@@H](O[C@@H]2[C@@H](C)[C@H](O[C@H]3C[C@@](C)(OC)[C@@H](O)[C@H](C)O3)[C@@H](C)C(=O)O[C@H](CC)[C@@](C)(O)[C@H](O)[C@@H](C)CN(CCC)[C@H](C)C[C@@]2(C)O)[C@@H]1O

Smiles: CN(C)[C@H]1C[C@@H](C)O[C@@H](O[C@@H]2[C@@H](C)[C@H](O[C@H]3C[C@@](C)(OC)[C@@H](O)[C@H](C)O3)[C@@H](C)C(=O)O[C@H](CC)[C@@](C)(O)[C@H](O)[C@@H](C)CN(CCC)[C@H](C)C[C@@]2(C)O)[C@@H]1O

and appetite in obese or overweight individuals: A randomized clinical trial

Consistent with the effects on thermogenic and β-oxidation gene expression and body weights

InChiKey: CQTDZUSQSTUZDA-JSULTTGTSA-M

consistent with other published IAP inhibitors

Y 11 Size:Contact [email protected] for quotation Smiles: CN(C)[C@H]1C[C@@H](C)O[C@@H](O[C@@H]2[C@@H](C)[C@H](O[C@H]3C[C@@](C)(OC)[C@@H](O)[C@H](C)O3)[C@@H](C)C(=O)O[C@H](CC)[C@@](C)(O)[C@H](O)[C@@H](C)CN(CCC)[C@H](C)C[C@@]2(C)O)[C@@H]1OFocal adhesion kinases (FAKs) are non receptor tyrosine kinases that play roles in regulating diverse processes, including cell adhesion, spreading, migration, proliferation, and apoptosis. They are over expressed in many types of cancer. Y11 inhibits FAK1 autophosphorylation by blocking phosphorylation of Y397. At 100 M, it was shown to decrease cell viability of T47D breast cancer and C8161 melanoma cell lines. Product information CAS Number: