Amoxapine nocembrin chalcone Smiles: C[C@@H]1O[C@@H](O[C@H]([C@H](C=O)NC(C)=O)[C@H](O[C@@H]2O[C@H](CO)[C@H](O)[C@H](O[C@@]3(C[C@H](O)[C@@H](NC(C)=O)[C@@H](O3)[C@H](O)[C@H](O)CO)C(O)=O)[C@H]2O)[C@H](O)CO)[C@@H](O)[C@H](O)[C@@H]1O

Smiles: C[C@@H]1O[C@@H](O[C@H]([C@H](C=O)NC(C)=O)[C@H](O[C@@H]2O[C@H](CO)[C@H](O)[C@H](O[C@@]3(C[C@H](O)[C@@H](NC(C)=O)[C@@H](O3)[C@H](O)[C@H](O)CO)C(O)=O)[C@H]2O)[C@H](O)CO)[C@@H](O)[C@H](O)[C@@H]1O

Smiles: CCCC1C(=NN(C=1O)C1=CC=CC=N1)C1C=CC=CC=1

InChiKey: GAJCGHAUFHRSDD-UHFFFAOYSA-N

NSC 663284 inhibits NSD2 (IC50 of 170 nM) through a direct interaction with the catalytic SET domain (Kd of 370 nM)

and their respective IL-8-overexpressing variants colorectal cancer cell lines

Amoxapine nocembrin chalcone Smiles: C[C@@H]1O[C@@H](O[C@H]([C@H](C=O)NC(C)=O)[C@H](O[C@@H]2O[C@H](CO)[C@H](O)[C@H](O[C@@]3(C[C@H](O)[C@@H](NC(C)=O)[C@@H](O3)[C@H](O)[C@H](O)CO)C(O)=O)[C@H]2O)[C@H](O)CO)[C@@H](O)[C@H](O)[C@@H]1OAmoxapine is a tetracyclic antidepressant of the dibenzoxazepine family, though it is often classified as a secondary amine tricyclic antidepressant. Product information CAS Number: 14028 44 5 Molecular Weight: 313. 78 Formula: C17H16ClN3O Chemical Name: 13 chloro 10 (piperazin 1 yl) 2 oxa 9 azatricyclo[9. 4. 0. 0,]pentadeca 1(11),3,5,7,9,12,14 heptaene Smiles: ClC1=CC2C(=NC3=CC=CC=C3OC=2C=C1)N1CCNCC1 InChiKey: QWGDMFLQWFTERH UHFFFAOYSA N InChi: