In Vitro and in Silico Human Monoamine Oxidase Inhibitory Potential of Anthraquinones
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A recent study shows that OSU-03012 could enhance the susceptibility of (Bcr)-Abl mutant cell lines to imatinib-induced apoptosis
with IC50s of 1 μM
Gentiopicroside Catalog No.:M14742-10 In Vitro and in SilicoGentiopicroside (GE, Gentiopicrin), a naturally occurring iridoid glycoside, inhibits CYP2A6 and CYP2E1 with IC50 values of 21. 8g ml and 594g ml, respectively in human liver microsomes, and dose not inhibit CYP2C9, CYP2D6, CYP1A2 or CYP3A4 activities. Product information CAS Number: 20831 76 9 Molecular Weight: 356. 32 Formula: C16H20O9 Synonym: Gentiopicrin Chemical Name: 5 ethenyl 6 {[3,4,5 trihydroxy 6 (hydroxymethyl)oxan 2 yl]oxy} 1H,3H,5H,6H