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PPARy is significantly activated at a high concentration (10 μM) of TAK-559
as a consequence of increasing intracellular iron concentrations caused by blocked iron export in HEK293 cells
CAS Number: 1216685-32-3
Treatment of PC-3 cells with Bortezomib (100 nM) for 8 h results in the accumulation of cells in G2-M
InChi: InChI=1S/C26H35FN16O2/c27-15-5-3-14(4-6-15)21-40-42-43(41-21)12-20(45)32-16-7-9-17(10-8-16)33-24-37-25(39-26(38-24)36-23(30)31)34-18(13-1-2-13)11-19(44)35-22(28)29/h3-6
TUG-1375 Size:Contact [email protected] for quotation PPARy is significantly activated atTUG 1375 is an agonist of free fatty acid receptor 2 (FFA2 GPR43), with a pKi of 6. 69. TUG 1375 is inactive on FFA3, FFA4, PPAR, PPAR, PPAR, LXR or LXR. Product information CAS Number: 2247372 59 2 Molecular Weight: 442. 92 Formula: C22H19ClN2O4S Chemical Name: (2R,4R) 2 (2 chlorophenyl) 3 [4 (3,5 dimethyl 1,2 oxazol 4 yl)benzoyl] 1,3 thiazolidine 4 carboxylic acid Smiles: CC1ON=C(C)C=1C1=CC=C(C=C1)C(=O)N1[C@@H](CS[C@@H]1C1=CC=CC=C1Cl)C(O)=O
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