N-Acetyl calicheamicin - enediyne antitumor antibiotic. CAS# 108212-76-6 Size:2mg solid Cardamonin alleviates inflammatory bowel disease

Cardamonin alleviates inflammatory bowel disease by the inhibition of NLRP3 inflammasome activation via an AhR/Nrf2/NQO1 pathway

with Rho (Kd = 80 nM)

Cornett EM

CAS Number: 511-15-9

NHE-mediated pH(i) recovery was unaffected by 30 microM S0859

N-Acetyl calicheamicin - enediyne antitumor antibiotic. CAS# 108212-76-6 Size:2mg solid Cardamonin alleviates inflammatory bowel diseaseN Acetyl calicheamicin, CAS No. 108212 76 6, is a derivative of calicheamicin, and is a potent enediyne antitumor antibiotic. Calicheamicins target DNA and cause strand scission. Calicheamicins bind with DNA in the minor groove, wherein they then undergo a reaction analogous to the Bergman cyclization to generate a diradical species. This diradical, 1, 4 didehydrobenzene, then abstracts hydrogen atoms from the deoxyribose (sugar) backbone of DNA,