CERC-501 - CAS# 1174130-61-0 60224 6 µM confirming the inhibition

6 µM confirming the inhibition of NMDA receptors observed in electrophysiological experiments

(2010) Mol Cancer Ther

Activation of the PI3K/mTOR pathway promotes cell growth

2010 Jul 16

1-Dimethylethoxy)- 2

CERC-501 - CAS# 1174130-61-0 60224 6 µM confirming the inhibitionCERC 501, also known as JNJ 67953964, LY 2456302 and Aticaprant, CAS No. 1174130 61 0, is a potent, selective, short acting antagonist of the opioid receptor (KOR) (Ki = 0. 81 nM vs. 24. 0 nM and 155 nM for the opioid receptor (MOR) and opioid receptor (DOR). Aticaprant is under development for the treatment of major depressive disorder and substance use disorders including alcoholism, nicotine addiction, and illicit drug dependence. Aticaprant has