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Mikusova K
Smiles: CC(C)(C)[C@H](NC(=O)CCCCCC(=O)N1CCN(CC[C@H](CSC2C=CC=CC=2)NC2=CC=C(C=C2S(=O)(=O)C(F)(F)F)S(=O)(=O)NC(=O)C2C=CC(=CC=2)N2CCN(CC2)CC2CC(C)(C)CCC=2C2C=CC(Cl)=CC=2)CC1)C(=O)N1C[C@H](O)C[C@H]1C(=O)N[C@@H](C)C1C=CC(=CC=1)C1SC=NC=1C
Voltage-gated sodium channels initiate action potentials in brain neurons
stem cell renewal and cancer growth
It exhibits anti-proliferative effects on DU 145 cells independently of IGF-1 signaling (IC50 ~0
Thalidomide paverine hydrochloride Mikusova KThalidomide is a synthetic derivative of glutamic acid (alpha phthalimido glutarimide) with teratogenic, immunomodulatory, anti inflammatory and anti angiogenic properties. Thalidomide acts primarily by inhibiting both the production of tumor necrosis factor alpha (TNF alpha) in stimulated peripheral monocytes and the activities of interleukins and interferons. This agent also inhibits polymorphonuclear chemotaxis and monocyte phagocytosis. In
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