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S3I-201 treatment of somatotroph tumor xenografts (n=15) significantly attenuated tumor growth for the duration of the experiment
Formula: C17H15NO3
Molecular Weight: 547
BAY11 enhances OCT4 synthetic mRNA expression in adult human skin cells
Elayne Chan-Penebre
Ferrostatin-1 - Fer-1, Ferroptosis Inhibitor. CAS# 347174-05-4 size:2mg solid S3I-201 treatment of somatotroph tumorFerrostatin 1 (Fer 1), CAS No. 347174 05 4 , is a potent inhibitor of ferroptosis with an EC50 ~60 nM, identified by a HTS using erastin induced ferroptosis in HT 1080 cells. Ferroptosis is a unique iron dependent form of nonapoptotic cell death triggered by the oncogenic RAS selective lethal small molecule erastin. Ferroptosis is dependent upon intracellular iron, but not other metals, and is morphologically, biochemically, and genetically distinct
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