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BI-3406 Size:10mg solid and for urinary retention along

SKU: 55949453530

4.0
USD117.97 USD144.97

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Description

and for urinary retention along with other measures

InChi: InChI=1S/C19H20N2O3/c1-19(2

Int J Mol Med

Formula: C14H14N3NaO5

Formula: C13H20Cl4N2O3

BI-3406 Size:10mg solid and for urinary retention alongBI 3406 is Potent & Selective SOS1:: KRAS Inhibitor (IC50=5 nM), which Opens a New Approach for Treating KRAS Driven Tumours. BI 3406 selectively binds to SOS1 and blocks the interaction with KRAS, irrespective of the KRAS mutation. BI 3406 causes RAS GTP and pERK reduction and inhibits cell growth of KRAS mutated cell lines, carrying most of the typical KRAS mutations (i. e. G12D, G12V, G13D and others). BI 3406, when administered orally to tumour

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