Propargyl-PEG2-Tos facytine consistent with an inhibition of

consistent with an inhibition of both mTORC1 and mTORC2 complexes

2 mg/kg) treatment shows the Vdss is 390 mL/kg and the CL is 96 mL/h-kg

Pan-RAS-IN-1 administration results in inhibition of tumor growth over 15 days of treatment

9 nmol/mg of the enzyme at 2 h after IV administration

CAS Number: 39089-30-0

Propargyl-PEG2-Tos facytine consistent with an inhibition ofPropargyl PEG2 Tos is a PEG based PROTAC linker that can be used in the synthesis of PROTACs. Product information CAS Number: 145916 41 2 Molecular Weight: 254. 30 Formula: C12H14O4S Chemical Name: 2 (prop 2 yn 1 yloxy)ethyl 4 methylbenzene 1 sulfonate Smiles: CC1=CC=C(C=C1)S(=O)(=O)OCCOCC#C InChiKey: KTEIFCKZGZZTHP UHFFFAOYSA N InChi: InChI=1S C12H14O4S c1 3 8 15 9 10 16 17(13,14)12 6 4 11(2)5 7 12 h1,4 7H,8 10H2,2H3 Technical Data Appearance: Solid