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TRAM 39 13081 Pranlukast shows competitive antagonism against

SKU: 56990848915

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Description

Pranlukast shows competitive antagonism against the LTC4- and LTD4-induced contractions of guinea pig trachea and lung parenchymal strips with a pA2 range of 7

15β-Trihydroxy-11-oxo-lanosta-8-en-24→20 lactone is a natural compound that could be isolated from G

2-benzoxazol-3-yl)piperidin-1-yl]propoxy}-3-methoxyphenyl)ethan-1-ol

CAS Number: 145317-11-9

Formula: C21H25N3O3

TRAM 39 13081 Pranlukast shows competitive antagonism againstTRAM 39, 2 (2 chlorophenyl) 2, 2 diphenyl acetonitrile, is a potent, synthetic, selective inhibitor of intermediate conductance Ca2+ activated K+channels. TRAM 39 selectively block K Ca3 but do not inhibit other Ca2+ activated K+channels.[1,3] Intermediate conductance Ca2 activated K channels are the product of the IKCa1 genes and are important in regulating the membrane potential of colonic epithelial cells, and lymphocytes. The IKCa1 gene is also

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