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CP-724714 potently reduces the EGF-induced autophosphorylation of the chimera containing the erbB2 kinase domain at a concentration as low as 50 nmol/L (IC50=32 nM) but is markedly less potent against EGFR
Chemical Name: 2-{5H-chromeno[2
InChi: InChI=1S/C29H43NO4S/c1-17(2)22-14-25(20(7)8)27(26(15-22)21(9)10)16-28(31)30-35(32
InChiKey: KYRVNWMVYQXFEU-UHFFFAOYSA-N
Epub 2017 Nov 27
Diclofenac potassium - CAS# 15307-81-0 551 CP-724714 potently reduces the EGF-inducedDiclofenac potassium is a potent and nonselective anti inflammatory agent, acts as a COX inhibitor, with IC50s of 4 and 1. 3 nM for human COX 1 and COX 2 in CHO cells, and 5. 1 and 0. 84 M for ovine COX 1 and COX 2, respectively. Diclofenac potassium induces apoptosis of neural stem cells (NSCs) via the activation of the caspase cascade. Product information CAS Number: 15307 81 0 Molecular Weight: 334. 24 Formula: C14H10Cl2KNO2 Chemical Name:
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