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B-17 scid male mice) treatment regresses EJ-1 tumors in mice
Formula: C29H34FN5O5
Formula: C7H16O6S
4-dihydroxyphenyl)ethoxy]-3
113 nM) and H3-receptors (Ki = 12
Prexasertib dimesylate - CAS# 1234015-58-7 Size:Contact [email protected] for quotation B-17 scid male mice) treatmentPrexasertib dimesylate (LY2606368 dimesylate) is a selective, ATP competitive second generation checkpoint kinase 1 (CHK1) inhibitor with a Ki of 0. 9 nM and an IC50 of <1 nM. Prexasertib dimesylate inhibits CHK2 (IC50=8 nM) and RSK1 (IC50=9 nM). Prexasertib dimesylate causes double stranded DNA breakage and replication catastrophe resulting in apoptosis. Prexasertib dimesylate shows potent anti tumor activity. Product information CAS Number: 1234015
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