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66-tetrakis(hydroxymethyl)-33-[(1H-indol-3-yl)methyl]-95-methyl-57
MC-betaglucuronide-MMAE-2 is a drug-linker conjugate for ADC with potent antitumor activity by using MMAE (a tubulin polymerization inhibitor)
7721 and Hela cells (48 h)
ML348 and ML349 do not decrease cell viability
consistent with the observed effects on HSC activation
Cycloguanil hydrochloride 2979165 66-tetrakis(hydroxymethyl)-33-[(1H-indol-3-yl)methyl]-95-methyl-57Cycloguanil hydrochloride, the active metabolite of Proguanil, acts on malaria schizonts in erythrocytes and hepatocytes. Product information CAS Number: 152 53 4 Molecular Weight: 288. 18 Formula: C11H15Cl2N5 Chemical Name: 1 (4 chlorophenyl) 6,6 dimethyl 1,6 dihydro 1,3,5 triazine 2,4 diamine hydrochloride Smiles: Cl. CC1(C)N=C(N)N=C(N)N1C1C=CC(Cl)=CC=1 InChiKey: MOUAPRKJJUXEIE UHFFFAOYSA N InChi: InChI=1S C11H14ClN5. ClH c1 11(2)16 9(13)15
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