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a novel potent antagonist that selectively modulates native TRPC4/C5 ion channels
4 μM in C57BL/6 male mice
It inhibits proliferation of MLL-AF4 rearranged cell line MV4-11 with an IC50 of 9 nM
Bone morphogenic protein 1 (BMP1) is an enzyme responsible for the cleavage and maturation of growth factors and ECM proteins
pharmaceutically acceptable salts thereof and compositions containing said inhibitors for prophylaxis and treatment of viral diseases
Almitrine mesylate 8757 a novel potent antagonist thatAlmitrine mesylate (Almitrine bismesylate, Almitrine dimethanesulfonate, Almitrine dimesylate), a pharmacologically unique respiratory stimulant, acts as an agonist of peripheral chemoreceptors located on the carotid bodies. Almitrine mesylate inhibits the activity of Ca2+ dependent K+ channel by decreasing its open probability with IC50 of 0. 22 M. Product information CAS Number: 29608 49 9 Molecular Weight: 669. 76 Formula: C28H37F2N7O6S2 Synonym:
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