Timapiprant sodium (OC000459 sodium) (1 μM) inhibits the activation of Th2 cells and eosinophils in response to supernatants from IgE/anti-IgE-activated human mast cells
Smiles: CO[C@H]1C2=CC=C(O)C=C2OC[C@]1(O)CC1C=CC(O)=CC=1
Smiles: COC1C=C(C=CC=1O)[C@H]1OC[C@@H]2[C@H](OC[C@@H]21)C1C=C(OC)C(=CC=1)O[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O
Smiles: CC(C)CC1=CC=C(C=C1)C(C)C(O)=O
in contrast to loop L5-binding monastrol or α4/α6-binding BI8 which shows greater activity against basal Eg5 ATPase activity
N-(Azido-PEG2)-N-Boc-PEG4-NHS ester isolone farnesylate Timapiprant sodium (OC000459 sodium) (1N (Azido PEG2) N Boc PEG4 NHS ester is a PEG based PROTAC linker that can be used in the synthesis of PROTACs. Product information CAS Number: 2093153 95 6 Molecular Weight: 619. 66 Formula: C26H45N5O12 Chemical Name: 2,5 dioxopyrrolidin 1 yl 1 (13 azido 2,2 dimethyl 4 oxo 3,8,11 trioxa 5 azatridecan 5 yl) 3,6,9,12 tetraoxapentadecan 15 oate Smiles: CC(C)(C)OC(=O)N(CCOCCOCCN=[N+]=[N ])CCOCCOCCOCCOCCC(=O)ON1C(=O)CCC1=O InChiKey: JLYRAESBBJMWBK