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Discovery of Covalent CDK14 Inhibitors with Pan-TAIRE Family Specificity
(2012) Mol Cancer Ther
InChiKey: KJCVRFUGPWSIIH-UHFFFAOYSA-N
CAS Number: 150450-53-6
Solubility: Water: 29 mg/mL(194
Theaflavin 3, 3'-digallate Catalog No.:M18282-C Discovery of Covalent CDK14 InhibitorsTheaflavin 3,3' digallate (TF 3) is a potent Zika virus (ZIKV) protease inhibitor with an IC50 of 2. 3 M. Theaflavin 3,3' digallat directly binds to ZIKVpro (Kd=8. 86 M) and inhibits ZIKV replication. Theaflavin 3,3' digallat inhibits the activity of gp41 and NS2B 3 protease and has antiviral activity against HSV and HIV 1. Theaflavin 3,3' digallate, the typical pigment in black tea, is a potent antitumor agent. Product information CAS Number: 30462
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