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is an orally bioavailable farnesyltransferase inhibitor
Smiles: N#CNC1=NN=CS1
P5091 was used at 5-12
InChi: InChI=1S/C21H18Cl2N2O4/c1-28-15-5-2-13(3-6-15)18-19(24-8-10-29-11-9-24)21(27)25(20(18)26)14-4-7-16(22)17(23)12-14/h2-7
02 μM for BRD2(BD2)
MMP-2 Inhibitor II Size:Contact [email protected] for quotation is an orally bioavailable farnesyltransferaseMMP 2 Inhibitor II is an irreversible, potent and selective MMP 2 inhibitor with Ki value of 2. 4 M . Matrix metalloproteinases (MMPs) are zinc dependent endopeptidases that play important roles in physiological and pathological conditions. Two MMPs, gelatinases A and B (MMP 2 and MMP 9, respectively), is highly expressed in human cancer, and a direct relationship between cancer progression and gelatinase expression and activity has been well
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