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InChi: InChI=1S/C24H32O4/c1-14-12-18-19(22(4)9-6-17(27)13-21(14)22)7-10-23(5)20(18)8-11-24(23
PF 3084014
Coniglio SJ
A66 is a potent inhibitor of the wild-type and oncogenic forms of p110α but not other class-I PI3K isoforms
Cell Immunol
Larotrectinib sulfate 775riflophenone 3-C-glucoside InChi: InChI=1S/C24H32O4/c1-14-12-18-19(22(4)9-6-17(27)13-21(14)22)7-10-23(5)20(18)8-11-24(23Larotrectinib sulfate (LOXO 101 sulfate; ARRY 470 sulfate) is an ATP competitive oral, selective inhibitor of the tropomyosin related kinase (TRK) family receptors, with low nanomolar 50% inhibitory concentrations against all three isoforms (TRKA, B, and C). Product information CAS Number: 1223405 08 0 Molecular Weight: 526. 51 Formula: C21H24F2N6O6S Chemical Name: (3S) N {5 [(2R) 2 (2,5 difluorophenyl)pyrrolidin 1 yl]pyrazolo[1,5 a]pyrimidin 3 yl} 3
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