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InChi: InChI=1S/C16H17N3O4S/c1-8-7-24-15-11(14(21)19(15)12(8)16(22)23)18-13(20)10(17)9-5-3-2-4-6-9/h2-6
2-benzothiazol-3-yl)piperazin-1-yl]methyl}cyclohexyl)methyl]-4-azatricyclo[5
) inhibits tumor growth
6 and 1 μM respectively
Formula: C21H28N8O3S2
Dual PARP EGFR ligand for PROTAC Catalog No.:M17144-C InChi: InChI=1S/C16H17N3O4S/c1-8-7-24-15-11(14(21)19(15)12(8)16(22)23)18-13(20)10(17)9-5-3-2-4-6-9/h2-6Dual PARP EGFR ligand for PROTAC incorporates a ligand for PARP and EGFR , and a PROTAC linker, which recruit E3 ligases (such as VHL, CRBN, MDM2, and IAP). Dual PARP EGFR ligand for PROTAC can be used in the synthesis of DP C 4, which is CRBN based dual PROTAC for simultaneous degradation of EGFR and PARP. Product information Molecular Weight: 1020. 52 Formula: C53H56ClF2N9O8 Chemical Name: 6 ((4 ((3 chloro 4 fluorophenyl)amino) 7 methoxyquinazolin 6
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