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Chemical Name: N-(3-((2-((4-(4-methylpiperazin-1-yl)phenyl)amino)thieno[3
TUG-770 (Compound 22
Heclin does not block E2 binding but causes a conformational change that results in oxidation of the active site Cys
Blaquiere N
and the inhibition of USP14 is more pronounced
APTO-253 eptor Agonist Chemical Name: N-(3-((2-((4-(4-methylpiperazin-1-yl)phenyl)amino)thieno[3APTO 253 (LOR 253, LT 253) inhibits c Myc expression and selectively induces CDKN1A (p21), promotes G0 G1 cell cycle arrest, and triggers apoptosis in acute myeloid leukemia (AML) cells. APTO 253 is also an inducer of KLF4 (Krppel like factor 4). Product information CAS Number: 916151 99 0 Molecular Weight: 367. 38 Formula: C22H14FN5 Chemical Name: 2 (5 fluoro 2 methyl 1H indol 3 yl) 1H imidazo[4,5 f][1,10]phenanthroline Smiles:
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