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[H]/N=C(/N)\SCCC1C=CC(CCS/C(/N)=N/[H])=CC=1
Delamanid is insoluble in water and its activity was proven in several in vitro and in vivo studies
Smiles: OC1=C2N=CC=CC2=C(Cl)C=C1Cl
InChi: InChI=1S/C26H26N2O2/c1-30-26(29)25(16-22-17-27-24-15-9-8-14-23(22)24)28(18-20-10-4-2-5-11-20)19-21-12-6-3-7-13-21/h2-15
CAS Number: 131740-09-5
3-(4-Pyridyl)indole Catalog No.:M22402-C [H]/N=C(/N)\SCCC1C=CC(CCS/C(/N)=N/[H])=CC=13 (4 pyridyl)indole (Rockout) is a Rho kinase inhibitor . Rho associated protein kinase (ROCK) belongs to a family of serine threonine kinases mainly involved in regulating the shape and movement of cells by acting on the cytoskeleton . Rockout caused decreased migration and aberrant morphology. Rockout showed no effect on phagocytosis, listeria motility or actin polymerization in permeabilized yeast. In a human melanoma cell line M2 cells that blebs
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