The brain penetrant metabolite N-desmethylclozapine preferentially bound to M1 muscarinic receptors with an IC50 of 55 nM and was a more potent partial agonist (EC50
Lapatinib ditosylate monohydrate (GW572016 ditosylate monohydrate) is a potent inhibitor of the ErbB-2 and EGFR tyrosine kinase domains with IC50 values against purified EGFR and ErbB-2 of 10
Formula: C53H82O25
Solubility: DMSO : 250 mg/mL (507
42 nM [median]) and RSV B (IC50
6'-Iodoresiniferatoxin Catalog No.:M22278-C The brain penetrant metabolite N-desmethylclozapineProduct information CAS Number: 335151 55 8 Molecular Weight: 754. 60 Formula: C37H39IO9 Chemical Name: [(1R,2R,6R,10S,11R,13S,15R,17R) 13 benzyl 6 hydroxy 4,17 dimethyl 5 oxo 15 (prop 1 en 2 yl) 12,14,18 trioxapentacyclo[11. 4. 1. 0,. 0,. 0,]octadeca 3,8 dien 8 yl]methyl 2 (4 hydroxy 3 iodo 5 methoxyphenyl)acetate Smiles: C[C@@H]1C[C@@]2(O[C@@]3(CC4C=CC=CC=4)O[C@@H]2[C@@H]2C=C(C[C@@]4(O)[C@@H](C=C(C)C4=O)[C@@]12O3)COC(=O)CC1C=C(I)C(O)=C(C=1)OC)C(C)=C