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InChi: InChI=1S/C19H17N5O2
PubMed PMID: 22736948
binds convincingly within the ATP-binding site of Pim-1 suggesting an ATP-competitive inhibitory mechanism
bethoxazin may exert its microbicidal action by reacting with sensitive endogenous sulfhydryl biomolecules of microbial cells
Consistent with the inhibition of prosurvival AKT signaling
Telotristat 845 InChi: InChI=1S/C19H17N5O2Telotristat, also known as LP 778902, is the acid form of Telotristat ethyl, and the active metabolite of LX1606 (Telotristat etiprate), which is an orally bioavailable, small molecule, tryptophan hydroxylase (TPH) inhibitor and serotonin synthesis inhibitor with potential antiserotonergic activity. Blocking peripheral serotonin synthesis by telotristat reduces severity of both chemical and infection induced intestinal inflammation. Product