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G-749 shows antiproliferative activity by inducing apoptosis
TNKS2 IC50 = 15
mVEGFR-3 and B-RAF
Formula: C18H21FN2O
PubMed Central PMCID: PMC4573895
Coumermycin A1 - CAS# 4434-05-3 Catalog No.:M11727-2 G-749 shows antiproliferative activity byCoumermycin A1 is a JAK2 signal activator. Coumermycin A1 inhibits DNA Gyrase which thereby inhibits cell division in bacteria. Product information CAS Number: 4434 05 3 Molecular Weight: 1110. 08 Formula: C55H59N5O20 Chemical Name: (3R, 4S, 5R, 6R) 5 hydroxy 6 [(4 hydroxy 3 {5 [(4 hydroxy 7 {[(2R, 3R, 4S, 5R) 3 hydroxy 5 methoxy 6, 6 dimethyl 4 (5 methyl 1H pyrrole 2 carbonyloxy)oxan 2 yl]oxy} 8 methyl 2 oxo 2H chromen 3 yl)carbamoyl] 4 methyl 1H
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