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Apoptolidin is an apoptosis inducer and induces apoptotic cell death in cells transformed with the adenovirus type 12 oncogenes including ElA (IC50=10-17 ng/ml) but not in normal cells
inhibits the interaction between G-quadruplex (G4) and IGF-1 (Insulin-like growth factor type I)
PMID: 22715131
Phthalimide-PEG4-PDM-OTBS can be used in the synthesis of a series of PROTACs
Two indolocarbazole alkaloids with apoptosis activity from a marine-derived actinomycete Z2039-2 Arch
Impurity of Doxercalciferol n C sodium Apoptolidin is an apoptosis inducerImpurity of Doxercalciferol is an impurity of doxercalciferol, which is a synthetic analog of ergocalciferol (vitamin D2), used as a drug for secondary hyperparathyroidism and metabolic bone disease, and it suppresses parathyroid synthesis and secretion. Product information CAS Number: 127516 23 8 Molecular Weight: 412. 65 Formula: C28H44O2 Chemical Name: (1R,3R,5Z) 5 {2 [(1R,3aS,4E,7aR) 1 [(2R,3E,5R) 5,6 dimethylhept 3 en 2 yl] 1,3a dihydrogenio 7a