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AP-18 reversibly blocks mouse TRPA1 responses to iodoacetamide (an irreversible cysteine-alkylating agent) in CHO cells assayed by ratiometric Ca2+ imaging
Intramolecular Heck Reactions for the Synthesis of the Novel Antibiotic Mensacarcin: Investigation of Catalytic
Ac-RYYRIK-NH2 (intracerebroventricularly (i
Chemical Name: 1-methyl-3-{9-[(1-methylquinolin-1-ium-3-yl)carbamoyl]-1
Chemical Name: 5-hydroxy-2-(4-hydroxyphenyl)-4H-chromen-4-one
Rhein HPC-O-Ph-PEG1-NH-Boc AP-18 reversibly blocks mouse TRPA1Rhein is a lipophilic anthraquinone extensively found in medicinal herbs, and has many pharmacological effects, including epatoprotective, nephroprotective, anti inflammatory, antioxidant, anticancer, and antimicrobial activities. IC50 value: Target: In vitro: Rhein (0. 1 and 1 mg mL) evidently suppressed cell proliferation and mitogen activated protein (MAP) kinase activation in human colon adenocarcinoma cells (Caco 2) but significantly lessened