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CC-115 - CAS# 1228013-15-7 Catalog No.:M6483-10 2019 Feb 1

SKU: 7804199831

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Description

2019 Feb 1

Formula: C17H12Cl2N6O4

Stephen Willingham

is a novel and specific small molecule activator of cryptochrome (CRY) identified from an unbiased cell-based circadian screen (in human osteosarcoma U2OS cell line harboring a Bmal1-dLuc luciferase reporter)

(2007) Cancer Res

CC-115 - CAS# 1228013-15-7 Catalog No.:M6483-10 2019 Feb 1CC 115, CAS No. 1228013 15 7, is a dual inhibitor of DNA dependent protein kinase (DNA PK) and mammalian target of rapamycin (mTOR), with potential antineoplastic activity. CC 115 binds to and inhibits the activity of DNA PK and both raptor mTOR (TOR complex 1 or TORC1) and rictor mTOR (TOR complex 2 or TORC2), which may lead to a reduction in cellular proliferation of cancer cells expressing DNA PK and TOR. DNA PK, a serine threonine kinase and a

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